Urea Breath Test Infrared (UBIT™)

Message
Patient must be off antibiotics, proton-pump inhibitors; (ie. Prilosec™, Nexium™, Protonix™, Aciphex™, and Bismuth) preparations two weeks prior to administration of test.

Test Code
75181

CPT Codes
83013

Preferred Specimen
Human Breath: Paired breath samples (pre and post) collected in Meretek Kit bags and must be submitted together. Follow instructions provided with kit.

Instructions
Patient preparation: Patient should fast one hour before collection of baseline breath sample. Patient must be off antibiotics, proton-pump inhibitors; (ie. Prilosec™, Nexium™, Protonix™, Aciphex™, and Bismuth) preparations two weeks prior to administration of test. Pranactin®-Citric contains a small amount of aspartame sweetener. Test may not be suitable for patients with phenylketonuria whose dietary phenylalanine should be restricted. The test can only be performed on specimens from patients greater than 18 years old.

Transport Container
Capped Blue and Pink Breath Tek™ UBIT™ UBT collection bags

Transport Temperature
Room Temperature
For specimen integrity in the lock box click here

Specimen Stability
Room Temperature = 7 days
Refrigerated = unacceptable
Frozen = unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Reject specimen types other than Breath Tek bags. Reject specimens on patients younger than 18 years old. Refrigerated and/or frozen specimen.

Methodology
Infared Spectrophotometry

Setup Schedule
Monday - Friday
BS

Report Available
1 day

Reference Range

SEX	AGE	Report Normals
N/M/F	1000Y	Negative

Clinical Significance
Helicobacter pylori is a gram-negative microaerophilic curved bacillus with an affinity for human gastric mucosa. H. pylori has been identified as an important pathogen in the upper GI tract. The relationship between H. pylori and chronic active gastritis, duodenal ulcers, and gastric ulcers has been well documented. BreathTek™ UBiT ® for H. pylori is a non-invasive, non-radioactive method for detecting urease activity associated with H. pylori infection. It is FDA approved to confirm cure and offers 95.2% sensitivity and 89.7% specificity compared with endoscopic methods.